**Calculation of Oral Morphine Equivalents (OME)**

Opioid |
Route |
Dose in commonly used Unit |
Multiplication Factor to get OME |
Oral Morphine Equivalents |

Alfentanil | IV | mg | 30 | 30mg |

Buprenorphine | PO/ SL/ buccal | 1mg | 30 | 30mg |

Buprenorphine | IV/IM | 1mg | 100 | 100mg |

Buprenorphine | Transdermal | 1 mcg/h | 75 | 1.8mg/d (75mcg/h) |

**Aug 13 2022**

##
How do you calculate morphine equivalents?

- Calculate the 24 hour current dose: 90mg q 12 = 180 mg Morphine/24 hours
- Use the oral to parenteral equianalgesic ratio: 30 mg PO Morphine = 10 mg IV Morphine
- Calculate new dose using ratios: 180/30 x 10 = 60 mg IV Morphine/24 hours or 2.5 mg/hour infusion

##
How to determine morphine equivalents?

**Morphine** **Equivalent** Dosing RxPerts Industry Insights 3 Do the Math Milligram **Morphine** **Equivalent** (MME) is a value assigned to opioids to represent their relative potencies. MME is determined by using an equivalency factor to **calculate** a dose of **morphine** that is **equivalent** to the ordered **opioid**. Daily MED is the sum of

##
Which is stronger morphine or oxycodone?

Oxycodone is 50 percent stronger than morphine. It’s prescribed and abused similarly to hydrocodone and maybe a bit more dangerous since it’s more potent. You can get oxycodone alone (OxyContin, Roxicodone) or oxycodone/acetaminophen (Percocet). Methadone is three times more potent than morphine.

##
What is a substitute for morphine?

Scientists have developed a new drug that could be a safer alternative to morphine for medical use. The researchers found that engineered variants of endomorphin, a naturally occurring chemical in the body, are as strong as morphine when it comes to killing pain.

What is a MED conversion calculator?

The Morphine Equivalent Dose** ( **MED) conversions calculator** allows a clinician to generate an equivalent dose of morphine for a patient taking one or more common opioids. ** This tool also provides precise control over methadone conversions as well.

Is equianalgesic ratio crude?

**Published equianalgesic ratios are considered crude estimates at best and therefore ** it is imperative that careful consideration is given to individualizing the dose of the selected opioid. Dosage titration of the new opioid should be completed slowly and with frequent monitoring.