Calculation of Oral Morphine Equivalents (OME)
| Opioid | Route | Dose in commonly used Unit | Multiplication Factor to get OME | Oral Morphine Equivalents |
| Alfentanil | IV | mg | 30 | 30mg |
| Buprenorphine | PO/ SL/ buccal | 1mg | 30 | 30mg |
| Buprenorphine | IV/IM | 1mg | 100 | 100mg |
| Buprenorphine | Transdermal | 1 mcg/h | 75 | 1.8mg/d (75mcg/h) |
Aug 13 2022
How do you calculate morphine equivalents?
- Calculate the 24 hour current dose: 90mg q 12 = 180 mg Morphine/24 hours
- Use the oral to parenteral equianalgesic ratio: 30 mg PO Morphine = 10 mg IV Morphine
- Calculate new dose using ratios: 180/30 x 10 = 60 mg IV Morphine/24 hours or 2.5 mg/hour infusion
How to determine morphine equivalents?
Morphine Equivalent Dosing RxPerts Industry Insights 3 Do the Math Milligram Morphine Equivalent (MME) is a value assigned to opioids to represent their relative potencies. MME is determined by using an equivalency factor to calculate a dose of morphine that is equivalent to the ordered opioid. Daily MED is the sum of
Which is stronger morphine or oxycodone?
Oxycodone is 50 percent stronger than morphine. It’s prescribed and abused similarly to hydrocodone and maybe a bit more dangerous since it’s more potent. You can get oxycodone alone (OxyContin, Roxicodone) or oxycodone/acetaminophen (Percocet). Methadone is three times more potent than morphine.
What is a substitute for morphine?
Scientists have developed a new drug that could be a safer alternative to morphine for medical use. The researchers found that engineered variants of endomorphin, a naturally occurring chemical in the body, are as strong as morphine when it comes to killing pain.
What is a MED conversion calculator?
The Morphine Equivalent Dose ( MED) conversions calculator allows a clinician to generate an equivalent dose of morphine for a patient taking one or more common opioids. This tool also provides precise control over methadone conversions as well.
Is equianalgesic ratio crude?
Published equianalgesic ratios are considered crude estimates at best and therefore it is imperative that careful consideration is given to individualizing the dose of the selected opioid. Dosage titration of the new opioid should be completed slowly and with frequent monitoring.