Precautions

Withdrawn over reports of increased risk of stroke, reinstated after increased risk not found. Serious hepatotoxicity leading to liver transplant or death. Not approved in the US, withdrawn in France in 1994 and the rest of the market in 1995 because of rare but serious hepatotoxicity.

Why was bromfed discontinued?

Bromfed DM is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu. Bromfed DM will not treat a cough that is caused by smoking, asthma, or emphysema. Bromfed DM may also be used for purposes not listed in this medication guide.

What conditions does bromfed DM treat?

While Bromfed DM usually makes adults drowsy, it can have the opposite effect in children and make them very excited and hyper. If your child is having trouble sleeping after starting this medication, speak with their provider to discuss better options. WORSENING OF SPECIFIC HEALTH CONDITIONS

Does bromfed make you drowsy?

Bromfed ® DM Cough Syrup is a clear, light pink-colored, butterscotch-flavored syrup containing in each 5 mL (1 teaspoonful) brompheniramine maleate 2 mg, pseudoephedrine hydrochloride 30 mg and dextromethorphan hydrobromide 10 mg, available in the following sizes: 4 fl oz (118 mL) NDC 60432-837-04 1 Pint (473 mL) NDC 60432-837-16

What does bromfed DM have in it?

What is the over-the-counter version of Bromfed?

Brompheniramine/dextromethorphan/pseudoephedrine is an over-the-counter (OTC) product used for relief of nasal congestion and cough. Brompheniramine/dextromethorphan/pseudoephedrine is available under the following different brand names: Bromfed-DM.

Can you buy Bromfed DM over-the-counter?

Bromfed DM is only available on a prescription from your doctor. This is because it contains pseudoephedrine, a sought after ingredient for the illicit manufacture of methamphetamine.

Is Bromfed and Dimetapp the same?

Brompheniramine/dextromethorphan/phenylephrine is an over-the-counter (OTC) product used for relief of cold symptoms. Brompheniramine/dextromethorphan/phenylephrine is available under the following different brand names: Neo DM Suspension, Dimaphen DM, and Children’s Dimetapp Cold & Cough.

Can you buy Bromphen over-the-counter?

Some common kinds you can buy over the counter include: Brompheniramine (one brand name: Children’s Dimetapp Cold) Dimenhydrinate (one brand name: Dramamine) Diphenhydramine (three brand names: Benadryl, Nytol, Sominex)

What is the best cough suppressant over the counter?

Cough SuppressantsMedicationsPercentage of Pharmacists’ Votes#1 Delsym Most Pharmacist Votes47%View on Amazon#2 Mucinex DM32%View on Amazon#3 Robitussin15%View on Amazon#4 NyQuil6%View on Amazon1 more row

What is in Bromfed DM cough syrup?

Brompheniramine maleate 2mg, pseudoephedrine HCl 30mg, dextromethorphan HBr 10mg; per 5mL; liq; contains alcohol 0.95% v/v; butterscotch flavor.

Why was Dimetapp discontinued?

Children’s Robitussin and Dimetapp cough medicines recalled due to potential overdose risks.

Is brompheniramine the same as Benadryl?

Benadryl (Diphenhydramine) is great for allergies, but curl up on the couch after taking it and get ready for a nap. Brotapp (Pseudoephedrine / Brompheniramine) is a combination medicine that relieves cold and allergy symptoms. It’s good to use if you have congestion, watery eyes, and sneezing.

Is Bromfed discontinued?

Bromfed DM (Brompheniramine, Dextromethorphan, And Pseudoephedrine) This drug is obsolete.

What is a good substitute for pseudoephedrine?

Hello! Second, there is an effective alternative, phenylephrine (PE). No drug is without some side effects, but PE’s side effects are much milder, and you cannot make meth out of it.

What kind of cough medicine is Bromfed?

What is Bromfed DM? Brompheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Dextromethorphan is a cough suppressant.

Is Bromfed a cough suppressant?

This combination medication is used to treat symptoms caused by the common cold, flu, allergies, hay fever, or other breathing illnesses (such as sinusitis, bronchitis). Dextromethorphan is a cough suppressant that affects a certain part of the brain (cough center), reducing the urge to cough.

Can you take dimetapp with Bromfed?

The cause of the interaction is not known. When these two medicines are taken together, your body may be more sensitive to the blood pressure effects of appetite suppressants, or to medicines used to treat a stuffy nose, cold, or heart condition.

Does Bromfed help with cough?

Bromfed DM (brompheniramine / dextromethorphan / pseudoephedrine) Bromfed DM is an affordable and effective option for treating cough and cold symptoms, but unlike similar alternatives, it’s not available over-the-counter.

What is the main ingredient in dimetapp?

In Each 10 Ml Active Ingredients: Brompheniramine Maleate, USP (2 Mg), Antihistamine; Dextromethorphan HBr, USP (10 Mg), Cough Suppressant; Phenylephrine HCl, USP (5 Mg), Nasal Decongestant.

How long does it take for Bromfed to kick in?

The onset of antitussive action occurs in 15 to 30 minutes after administration and is of long duration.

Before Taking This Medicine

Do not use Bromfed DM if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isoc…

How Should I Take Bromfed DM?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Coug…

What Happens If I Miss A Dose?

Since this medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as…

What Should I Avoid While Taking Bromfed DM?

Drinking alcohol can increase certain side effects of brompheniramine, dextromethorphan, and pseudoephedrine.Ask a doctor or pharmacist before usin…

What Other Drugs Will Affect This Medicine?

Tell your doctor about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines…

How should I take Bromfed DM?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cough or cold medicine is usually taken only for a short time until your symptoms clear up.

What is brompheniramine?

Brompheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Why does DM cause a stuffy nose?

Dilated blood vessels can cause nasal congestion (stuffy nose). Bromfed DM is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu. Bromfed DM will not treat a cough that is caused by smoking, asthma, or emphysema.

How to measure liquid medicine?

Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Can you take Bromfed DM if you missed it?

Since Bromfed DM is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Can bromfed DM harm a baby?

It is not known whether Bromfed DM will harm an unborn baby. Do not use this medicine without a doctor’s advice if you are pregnant. This medicine can pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production.

Can bromfed DM be taken with sleep pills?

Ask your doctor before taking Bromfed DM with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

What is bromfed DM?

Bromfed DM – Clinical Pharmacology. Brompheniramine maleate is a histamine antagonist, specifically an H1-receptor-blocking agent belonging to the alkylamine class of antihistamines. Antihistamines appear to compete with histamine for receptor sites on effector cells.

How long does it take for brompheniramine to be absorbed?

Brompheniramine is well absorbed from the gastrointestinal tract, with peak plasma concentration after single, oral dose of 4 mg reached in 5 hours; urinary excretion is the major route of elimination, mostly as products of biodegradation; the liver is assumed to be the main site of metabolic transformation.

What are the interactions between MAO inhibitors and antihistamines?

Hyperpyrexia, hypotension, and death have been reported coincident with the coadministration of MAO inhibitors and products containing dextromethorphan. In addition, MAO inhibitors prolong and intensify the anticholinergic (drying) effects of antihistamines and may enhance the effect …

Does bromfed cause fertility issues?

Reproduction studies of brompheniramine maleate (a component of Bromfed® DM Cough Syrup) in rats and mice at doses up to 16 times the maximum human doses have revealed no evidence of impaired fertility or harm to the fetus.

Can you give bromfed to a pregnant woman?

It should be given to a pregnant woman only if clearly needed. Reproduction studies of brompheniramine maleate (a component of Bromfed® DM Cough Syrup) in rats and mice at doses up to 16 times the maximum human doses have revealed no evidence of impaired fertility or harm to the fetus.

Can you take dextromethorphan in a newborn?

Do not use dextromethorphan in patients receiving monoamine oxidase (MAOI) inhibitors (see PRECAUTIONS – Drug Interactions ).

When to induce emesis?

Induce emesis if patient is alert and is seen prior to 6 hours following ingestion. Precautions against aspiration must be taken, especially in infants and small children. Gastric lavage may be carried out, although in some instances tracheostomy may be necessary prior to lavage.

What are the components of bromfed?

Ok. Bromfed has three components : antihistamine, decongestant and cough suppressant. Over the counter, I couldn’t find one product that has all three things. You can combine products to get the same effect though.

How much Guaifenesin is in mucinex?

Pills make easier to take higher dose. Mucinex tablets can have 1200mg of guaifenesin where as syrup don’t have that much

What Is Brompheniramine/Dextromethorphan/Pseudoephedrine and How Does It Work?

Brompheniramine/ dextromethorphan / pseudoephedrine is an over-the-counter ( OTC) product used for relief of nasal congestion and cough.

How many drugs interact with brompheniramine?

Severe interactions of brompheniramine/dextromethorphan/pseudoephedrine include: Brompheniramine/dextromethorphan/pseudoephedrine has serious interactions with at least 54 different drugs. Brompheniramine/dextromethorphan/pseudoephedrine has moderate interactions with at least 273 different drugs.

Can you take brompheniramine while breastfeeding?

Brompheniramine/dextromethorphan/pseudoephedrine is excreted in breast milk. It is not recommended for use while breastfeeding. Pregnant or breastfeeding patients should seek advice of a health professional before using over-the-counter (OTC) drugs.

Is brompheniramine excreted in breast milk?

Brompheniramine/dextromethorphan/pseudoephedrine is excreted in breast milk. It is not recommended for use while breastfeeding.

Can bromfed DM be taken with brompheniramine?

Do not take Bromfed-DM if you are allergic to brompheniramine/dextromethorphan/pseudoephedrine or any ingredients contained in this drug. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

Can brompheniramine cause confusion?

Brompheniramine: May cause significant confusional symptoms; not for administration to premature or full-term neonates

What is bromfed DM?

Bromfed DM. BROMPHENIRAMINE; DEXTROMETHORPHAN; PSEUDOEPHEDRINE is a histamine blocker, cough suppressant, and a decongestant. It can help relieve cough, runny nose, stuffy nose, sneezing, and itchy or watery eyes. This medicine is used to treat allergy and cold symptoms. This medicine will not treat an infection.

Is it worth asking your doctor about generics?

If you’re taking an expensive brand-name-only drug, it may be worth asking your doctor if there are any other less expensive, generic, or over-the-counter options that might work for you.

What is bromfed DM cough syrup?

Bromfed DM Cough Syrup is indicated for relief of cough and upper respiratory symptoms, including nasal congestion, associated with allergy or the common cold.

What are the adverse reactions to DM cough syrup?

The most frequent adverse reactions to Bromfed DM Cough Syrup are sedation; dryness of mouth, nose, and throat; thickening of bronchial secretions; and dizziness

Is bromfed DM a narcotic?

Bromfed DM is the ONLY FDA-approved, non-narcotic prescription product containing pseudoephedrine that is indicated for relief of cough and upper respiratory symptoms associated with allergy or the common cold. 5.

Can you use bromfed cough syrup in a newborn?

Bromfed DM Cough Syrup should not be used in newborns, in premature infants, in nursing mothers, or in patients with severe hypertension or severe coronary artery disease. Bromfed DM Cough Syrup should not be used in patients receiving monoamine oxidase (MAO) inhibitors.

Can brompheniramine cause confusion?

Brompheniramine: May cause significant confusional symptoms; not for administration to premature or full-term neonates

Does brompheniramine increase albuterol?

brompheniramine increases and albuterol decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

Does brompheniramine cause seizures?

Modify Therapy/Monitor Closely. Comment: Amifampridine can cause seizures. Coadministration with drugs that lower seizure threshold may increase this risk.

Does abiraterone increase dextromethorphan?

Monitor Closely (1) abiraterone increases levels of dextromethorphan by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Avoid coadministration of abiraterone with substrates of CYP2D6. If alternative therapy cannot be used, exercise caution and consider a dose reduction of the CYP2D6 substrate.